TRASTUZUMABUM DERUXTECANUM
Účinná látka · 1 přípravek na trhu
- Mezinárodní název
- TRASTUZUMABUM DERUXTECANUM
- Český název
- TRASTUZUMAB DERUXTEKAN
- Anglicky
- TRASTUZUMAB DERUXTECAN
Synonyma: 1826843-81-5 · IMMUNOGLOBULIN G1-KAPPA, ANTI-[HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)], HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO DERUXTECAN, COMPRISING A LINKER AND A CAMPTOTHECIN DERIVATIVE; GAMMA1 HEAVY CHAIN (1-450) [HUMANIZED VH (HOMO SAPIENS IGHV3-66*01 (81.60%) -(IGHD)-IGHJ4*02) [8.8.13] (1-120) -HOMO SAPIENS IGHG1*03V, G1M3>G1M17, NG1M1 (CH1 R120>K (217) (121-218), HINGE (219-233),CH2 (234-343), CH3 E12 (359), M14 (361) (344-448), CHS (449-450)) (121-450)], (223-214')- DISULFIDE WITH KAPPA LIGHT CHAIN (1'-214') [HUMANIZED V-KAPPA (HOMO SAPIENS IGKV1-39*01 (86.20%) -IGKJ1*01) [6.3.9] (1'-107') -HOMO SAPIENS IGKC*01, KM3 A45.1, V101 (108'-214')]; DIMER (229-229":232-232")-BISDISULFIDE; CONJUGATED, ON AN AVERAGE OF 8 CYSTEINYL, TO DERUXTECAN, COMPRISING A LINKER AND A CAMPTOTHECIN DERIVATIVE, RECOMMENDED INN: LIST 78 · TRASTUZUMAB DERUXTECAN · TRASTUZUMAB DERUXTEKAN · TRASTUZUMABUM DERUXTECANUM
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